Fare Guide

Estimated lowest fares found within 7 days

Cheapest Airline American Airlines

The cheapest airline(s) flying from Greenville to Detroit is American Airlines.

  • American Airlines American Airlines
  • Southwest Airlines Southwest Airlines
  • United Airlines United Airlines
Cheapest Month January

Travel Period: January 2025 - December 2025

The cheapest month(s) to fly from Greenville to Detroit is January.

  • Jan 2025
  • Feb 2025
  • Mar 2025
  • Apr 2025
  • May 2025
  • Jun 2025
  • Jul 2025
  • Aug 2025
  • Sep 2025
  • Oct 2025
  • Nov 2025
  • Dec 2025
Cheapest Day of the Week Saturday

The cheapest day(s) of the week to fly from Greenville to Detroit is Saturday.

  • Sun Sunday
  • Mon Monday
  • Tue Tuesday
  • Wed Wednesday
  • Thu Thursday
  • Fri Friday
  • Sat Saturday

Flight Schedules

Last Updated: Mon, 2 Dec, 2024

  • Time Earliest
    • Earliest
    • Latest
  • Depart Earliest
    • Earliest
    • Latest
  • Arrive
    • Earliest
    • Latest
  • Duration
    • Shortest
    • Longest
  • Stopover
    All
    • Airline Filter by Airline
      View All Airline
      • Availability
        • M
        • T
        • W
        • T
        • F
        • S
        • S
      • 19:30 GSP
        00:30 DTW
        5Hrs, 00m 1 Stop (BWI)
      • GSPGreenville/Spartanburg Airport 19:30 - DTW 00:30 5h 1 Stop (BWI) Baltimore
      • GSPGreenville/Spartanburg Airport 19:30
        BWIBaltimore Washington International Airport 22:55
      • BWIBaltimore Washington International Airport 21:00
        DTWDetroit Wayne County 00:30
      • 5h (1h 55m)
      • 1 Stop BWI · Baltimore 1h 55m
      • Southwest Airlines (WN 963)Boeing 737 700
        Southwest Airlines (WN 1431)Boeing 737 800
      • Southwest Airlines (WN 963)
        • -
        • -
        • -
        • -
        • -
        • S
        • -
      • 19:45 GSP
        23:56 DTW
        4Hrs, 11m 1 Stop (DCA)
      • GSPGreenville/Spartanburg Airport 19:45 - DTW 23:56 4h 11m 1 Stop (DCA) Washington
      • GSPGreenville/Spartanburg Airport 19:45
        DCAWashington Ronald Reagan National Airport 22:08
      • DCAWashington Ronald Reagan National Airport 21:20
        DTWDetroit Wayne County 23:56
      • 4h 11m (48m)
      • 1 Stop DCA · Washington 48m
      • American Airlines (AA 5038)Crj 700 Canadair Regional
        American Airlines (AA 5446)Crj 700 Canadair Regional
      • American Airlines (AA 5038)
        • M
        • -
        • -
        • T
        • F
        • -
        • S
      • 19:50 GSP
        23:59 DTW
        4Hrs, 09m 1 Stop (IAD)
      • GSPGreenville/Spartanburg Airport 19:50 - DTW 23:59 4h 09m 1 Stop (IAD) Washington
      • GSPGreenville/Spartanburg Airport 19:50
        IADWashington Dulles International Airport 22:15
      • IADWashington Dulles International Airport 21:25
        DTWDetroit Wayne County 23:59
      • 4h 09m (50m)
      • 1 Stop IAD · Washington 50m
      • United Airlines (UA 4313)Embraer
        United Airlines (UA 3527)Embraer 175
      • United Airlines (UA 4313)
        • M
        • T
        • W
        • T
        • F
        • S
        • S
      • 05:16 GSP
        09:13 DTW
        3Hrs, 57m 1 Stop (CLT)
      • GSPGreenville/Spartanburg Airport 05:16 - DTW 09:13 3h 57m 1 Stop (CLT) Charlotte
      • GSPGreenville/Spartanburg Airport 05:16
        CLTCharlotte Airport 07:27
      • CLTCharlotte Airport 06:26
        DTWDetroit Wayne County 09:13
      • 3h 57m (1h 01m)
      • 1 Stop CLT · Charlotte 1h 01m
      • American Airlines (AA 5344)Crj 700 Canadair Regional
        American Airlines (AA 1019)Airbus
      • American Airlines (AA 5344)
        • -
        • T
        • -
        • -
        • -
        • -
        • -
      • 05:16 GSP
        09:24 DTW
        4Hrs, 08m 1 Stop (CLT)
      • GSPGreenville/Spartanburg Airport 05:16 - DTW 09:24 4h 08m 1 Stop (CLT) Charlotte
      • GSPGreenville/Spartanburg Airport 05:16
        CLTCharlotte Airport 07:35
      • CLTCharlotte Airport 06:26
        DTWDetroit Wayne County 09:24
      • 4h 08m (1h 09m)
      • 1 Stop CLT · Charlotte 1h 09m
      • American Airlines (AA 5344)Crj 700 Canadair Regional
        American Airlines (AA 1019)Airbus
      • American Airlines (AA 5344)
        • M
        • -
        • -
        • T
        • F
        • S
        • S
      • 05:16 GSP
        11:05 DTW
        5Hrs, 49m 1 Stop (CLT)
      • GSPGreenville/Spartanburg Airport 05:16 - DTW 11:05 5h 49m 1 Stop (CLT) Charlotte
      • GSPGreenville/Spartanburg Airport 05:16
        CLTCharlotte Airport 09:15
      • CLTCharlotte Airport 06:26
        DTWDetroit Wayne County 11:05
      • 5h 49m (2h 49m)
      • 1 Stop CLT · Charlotte 2h 49m
      • American Airlines (AA 5344)Crj 700 Canadair Regional
        American Airlines (AA 615)Boeing 737 800
      • American Airlines (AA 5344)
        • M
        • -
        • -
        • T
        • F
        • -
        • S
      • 05:16 GSP
        11:09 DTW
        5Hrs, 53m 1 Stop (CLT)
      • GSPGreenville/Spartanburg Airport 05:16 - DTW 11:09 5h 53m 1 Stop (CLT) Charlotte
      • GSPGreenville/Spartanburg Airport 05:16
        CLTCharlotte Airport 09:19
      • CLTCharlotte Airport 06:26
        DTWDetroit Wayne County 11:09
      • 5h 53m (2h 53m)
      • 1 Stop CLT · Charlotte 2h 53m
      • American Airlines (AA 5344)Crj 700 Canadair Regional
        American Airlines (AA 615)Boeing 737 800
      • American Airlines (AA 5344)
        • -
        • T
        • -
        • -
        • -
        • -
        • -
      • 06:00 GSP
        10:59 DTW
        4Hrs, 59m 1 Stop (EWR)
      • GSPGreenville/Spartanburg Airport 06:00 - DTW 10:59 4h 59m 1 Stop (EWR) New York City
      • GSPGreenville/Spartanburg Airport 06:00
        EWRNewark Liberty International Airport 08:54
      • EWRNewark Liberty International Airport 07:59
        DTWDetroit Wayne County 10:59
      • 4h 59m (55m)
      • 1 Stop EWR · New York City 55m
      • United Airlines (UA 3695)Embraer 175
        United Airlines (UA 4420)Canadair Regional Jet 550
      • United Airlines (UA 3695)
        • -
        • T
        • W
        • T
        • F
        • -
        • -
      • 06:00 GSP
        11:01 DTW
        5Hrs, 01m 1 Stop (EWR)
      • GSPGreenville/Spartanburg Airport 06:00 - DTW 11:01 5h 01m 1 Stop (EWR) New York City
      • GSPGreenville/Spartanburg Airport 06:00
        EWRNewark Liberty International Airport 08:54
      • EWRNewark Liberty International Airport 08:01
        DTWDetroit Wayne County 11:01
      • 5h 01m (53m)
      • 1 Stop EWR · New York City 53m
      • United Airlines (UA 3695)Embraer 175
        United Airlines (UA 3502)Embraer 175
      • United Airlines (UA 3695)
        • M
        • -
        • -
        • -
        • -
        • -
        • -
      • 06:00 GSP
        11:05 DTW
        5Hrs, 05m 1 Stop (EWR)
      • GSPGreenville/Spartanburg Airport 06:00 - DTW 11:05 5h 05m 1 Stop (EWR) New York City
      • GSPGreenville/Spartanburg Airport 06:00
        EWRNewark Liberty International Airport 09:00
      • EWRNewark Liberty International Airport 07:59
        DTWDetroit Wayne County 11:05
      • 5h 05m (1h 01m)
      • 1 Stop EWR · New York City 1h 01m
      • United Airlines (UA 3695)Embraer 175
        United Airlines (UA 4420)Canadair Regional Jet 550
      • United Airlines (UA 3695)
        • -
        • -
        • -
        • -
        • -
        • -
        • S
      • 06:00 GSP
        11:08 DTW
        5Hrs, 08m 1 Stop (EWR)
      • GSPGreenville/Spartanburg Airport 06:00 - DTW 11:08 5h 08m 1 Stop (EWR) New York City
      • GSPGreenville/Spartanburg Airport 06:00
        EWRNewark Liberty International Airport 09:03
      • EWRNewark Liberty International Airport 08:01
        DTWDetroit Wayne County 11:08
      • 5h 08m (1h 02m)
      • 1 Stop EWR · New York City 1h 02m
      • United Airlines (UA 3695)Embraer 175
        United Airlines (UA 4420)Canadair Regional Jet 550
      • United Airlines (UA 3695)
        • -
        • -
        • -
        • -
        • -
        • S
        • -
      • 06:00 GSP
        11:31 DTW
        5Hrs, 31m 1 Stop (LGA)
      • GSPGreenville/Spartanburg Airport 06:00 - DTW 11:31 5h 31m 1 Stop (LGA) New York City
      • GSPGreenville/Spartanburg Airport 06:00
        LGANew York La Guardia Airport 09:29
      • LGANew York La Guardia Airport 07:54
        DTWDetroit Wayne County 11:31
      • 5h 31m (1h 35m)
      • 1 Stop LGA · New York City 1h 35m
      • American Airlines (AA 4751)Embraer Emb 175
        American Airlines (AA 4339)Embraer 170
      • American Airlines (AA 4751)
        • M
        • -
        • -
        • -
        • -
        • -
        • -
      • 06:30 GSP
        11:05 DTW
        4Hrs, 35m 1 Stop (CLT)
      • GSPGreenville/Spartanburg Airport 06:30 - DTW 11:05 4h 35m 1 Stop (CLT) Charlotte
      • GSPGreenville/Spartanburg Airport 06:30
        CLTCharlotte Airport 09:15
      • CLTCharlotte Airport 07:42
        DTWDetroit Wayne County 11:05
      • 4h 35m (1h 33m)
      • 1 Stop CLT · Charlotte 1h 33m
      • American Airlines (AA 5304)Canadair Regional
        American Airlines (AA 615)Boeing 737 800
      • American Airlines (AA 5304)
        • M
        • -
        • -
        • T
        • F
        • -
        • S
      • 06:30 GSP
        11:09 DTW
        4Hrs, 39m 1 Stop (CLT)
      • GSPGreenville/Spartanburg Airport 06:30 - DTW 11:09 4h 39m 1 Stop (CLT) Charlotte
      • GSPGreenville/Spartanburg Airport 06:30
        CLTCharlotte Airport 09:19
      • CLTCharlotte Airport 07:42
        DTWDetroit Wayne County 11:09
      • 4h 39m (1h 37m)
      • 1 Stop CLT · Charlotte 1h 37m
      • American Airlines (AA 5304)Canadair Regional
        American Airlines (AA 615)Boeing 737 800
      • American Airlines (AA 5304)
        • -
        • T
        • W
        • -
        • -
        • -
        • -
      • 06:55 GSP
        10:55 DTW
        4Hrs, 00m 1 Stop (BWI)
      • GSPGreenville/Spartanburg Airport 06:55 - DTW 10:55 4h 1 Stop (BWI) Baltimore
      • GSPGreenville/Spartanburg Airport 06:55
        BWIBaltimore Washington International Airport 09:20
      • BWIBaltimore Washington International Airport 08:30
        DTWDetroit Wayne County 10:55
      • 4h (50m)
      • 1 Stop BWI · Baltimore 50m
      • Southwest Airlines (WN 1440)Boeing 737 700
        Southwest Airlines (WN 468)Boeing 737 Max 8 Passenger
      • Southwest Airlines (WN 1440)
        • -
        • -
        • -
        • -
        • -
        • S
        • -
      • 07:05 GSP
        12:55 DTW
        5Hrs, 50m 1 Stop (BWI)
      • GSPGreenville/Spartanburg Airport 07:05 - DTW 12:55 5h 50m 1 Stop (BWI) Baltimore
      • GSPGreenville/Spartanburg Airport 07:05
        BWIBaltimore Washington International Airport 11:20
      • BWIBaltimore Washington International Airport 08:40
        DTWDetroit Wayne County 12:55
      • 5h 50m (2h 40m)
      • 1 Stop BWI · Baltimore 2h 40m
      • Southwest Airlines (WN 3665)Boeing 737 700
        Southwest Airlines (WN 1431)Boeing 737 800
      • Southwest Airlines (WN 3665)
        • -
        • T
        • -
        • -
        • -
        • -
        • -
      • 07:25 GSP
        12:55 DTW
        5Hrs, 30m 1 Stop (BWI)
      • GSPGreenville/Spartanburg Airport 07:25 - DTW 12:55 5h 30m 1 Stop (BWI) Baltimore
      • GSPGreenville/Spartanburg Airport 07:25
        BWIBaltimore Washington International Airport 11:20
      • BWIBaltimore Washington International Airport 09:00
        DTWDetroit Wayne County 12:55
      • 5h 30m (2h 20m)
      • 1 Stop BWI · Baltimore 2h 20m
      • Southwest Airlines (WN 3665)Boeing 737 700
        Southwest Airlines (WN 1431)Boeing 737 800
      • Southwest Airlines (WN 3665)
        • -
        • -
        • W
        • -
        • -
        • -
        • -
      • 09:09 GSP
        14:40 DTW
        5Hrs, 31m 1 Stop (CLT)
      • GSPGreenville/Spartanburg Airport 09:09 - DTW 14:40 5h 31m 1 Stop (CLT) Charlotte
      • GSPGreenville/Spartanburg Airport 09:09
        CLTCharlotte Airport 12:54
      • CLTCharlotte Airport 10:14
        DTWDetroit Wayne County 14:40
      • 5h 31m (2h 40m)
      • 1 Stop CLT · Charlotte 2h 40m
      • American Airlines (AA 5274)Crj 700 Canadair Regional
        American Airlines (AA 1022)Boeing 737 800
      • American Airlines (AA 5274)
        • -
        • -
        • W
        • -
        • -
        • -
        • -
      • 09:12 GSP
        14:40 DTW
        5Hrs, 28m 1 Stop (CLT)
      • GSPGreenville/Spartanburg Airport 09:12 - DTW 14:40 5h 28m 1 Stop (CLT) Charlotte
      • GSPGreenville/Spartanburg Airport 09:12
        CLTCharlotte Airport 12:54
      • CLTCharlotte Airport 10:17
        DTWDetroit Wayne County 14:40
      • 5h 28m (2h 37m)
      • 1 Stop CLT · Charlotte 2h 37m
      • American Airlines (AA 5274)Crj 700 Canadair Regional
        American Airlines (AA 1022)Boeing 737 800
      • American Airlines (AA 5274)
        • -
        • T
        • -
        • -
        • -
        • -
        • -
      • 09:12 GSP
        14:45 DTW
        5Hrs, 33m 1 Stop (CLT)
      • GSPGreenville/Spartanburg Airport 09:12 - DTW 14:45 5h 33m 1 Stop (CLT) Charlotte
      • GSPGreenville/Spartanburg Airport 09:12
        CLTCharlotte Airport 13:00
      • CLTCharlotte Airport 10:17
        DTWDetroit Wayne County 14:45
      • 5h 33m (2h 43m)
      • 1 Stop CLT · Charlotte 2h 43m
      • American Airlines (AA 5274)Crj 700 Canadair Regional
        American Airlines (AA 1022)Boeing 737 800
      • American Airlines (AA 5274)
        • M
        • -
        • -
        • T
        • F
        • S
        • S
      • 10:50 GSP
        16:35 DTW
        5Hrs, 45m 1 Stop (BNA)
      • GSPGreenville/Spartanburg Airport 10:50 - DTW 16:35 5h 45m 1 Stop (BNA) Nashville
      • GSPGreenville/Spartanburg Airport 10:50
        BNANashville Airport 14:00
      • BNANashville Airport 11:10
        DTWDetroit Wayne County 16:35
      • 5h 45m (2h 50m)
      • 1 Stop BNA · Nashville 2h 50m
      • Southwest Airlines (WN 2859)Boeing 737 700
        Southwest Airlines (WN 2699)Boeing 737 700
      • Southwest Airlines (WN 2859)
        • -
        • -
        • -
        • -
        • -
        • S
        • -
      • 11:11 GSP
        14:40 DTW
        3Hrs, 29m 1 Stop (CLT)
      • GSPGreenville/Spartanburg Airport 11:11 - DTW 14:40 3h 29m 1 Stop (CLT) Charlotte
      • GSPGreenville/Spartanburg Airport 11:11
        CLTCharlotte Airport 12:54
      • CLTCharlotte Airport 12:15
        DTWDetroit Wayne County 14:40
      • 3h 29m (39m)
      • 1 Stop CLT · Charlotte 39m
      • American Airlines (AA 5381)Canadair Regional
        American Airlines (AA 1022)Boeing 737 800
      • American Airlines (AA 5381)
        • -
        • T
        • W
        • -
        • -
        • -
        • -
      • 11:11 GSP
        14:45 DTW
        3Hrs, 34m 1 Stop (CLT)
      • GSPGreenville/Spartanburg Airport 11:11 - DTW 14:45 3h 34m 1 Stop (CLT) Charlotte
      • GSPGreenville/Spartanburg Airport 11:11
        CLTCharlotte Airport 13:00
      • CLTCharlotte Airport 12:15
        DTWDetroit Wayne County 14:45
      • 3h 34m (45m)
      • 1 Stop CLT · Charlotte 45m
      • American Airlines (AA 5381)Canadair Regional
        American Airlines (AA 1022)Boeing 737 800
      • American Airlines (AA 5381)
        • M
        • -
        • -
        • T
        • F
        • S
        • S
      • 11:11 GSP
        16:55 DTW
        5Hrs, 44m 1 Stop (CLT)
      • GSPGreenville/Spartanburg Airport 11:11 - DTW 16:55 5h 44m 1 Stop (CLT) Charlotte
      • GSPGreenville/Spartanburg Airport 11:11
        CLTCharlotte Airport 15:13
      • CLTCharlotte Airport 12:15
        DTWDetroit Wayne County 16:55
      • 5h 44m (2h 58m)
      • 1 Stop CLT · Charlotte 2h 58m
      • American Airlines (AA 5381)Canadair Regional
        American Airlines (AA 3299)Airbus
      • American Airlines (AA 5381)
        • M
        • -
        • -
        • T
        • F
        • S
        • S
      • 12:50 GSP
        16:55 DTW
        4Hrs, 05m 1 Stop (CLT)
      • GSPGreenville/Spartanburg Airport 12:50 - DTW 16:55 4h 05m 1 Stop (CLT) Charlotte
      • GSPGreenville/Spartanburg Airport 12:50
        CLTCharlotte Airport 15:13
      • CLTCharlotte Airport 13:54
        DTWDetroit Wayne County 16:55
      • 4h 05m (1h 19m)
      • 1 Stop CLT · Charlotte 1h 19m
      • American Airlines (AA 5175)Canadair Regional
        American Airlines (AA 3299)Airbus
      • American Airlines (AA 5175)
        • M
        • -
        • -
        • T
        • F
        • S
        • S
      • 12:50 GSP
        18:35 DTW
        5Hrs, 45m 1 Stop (CLT)
      • GSPGreenville/Spartanburg Airport 12:50 - DTW 18:35 5h 45m 1 Stop (CLT) Charlotte
      • GSPGreenville/Spartanburg Airport 12:50
        CLTCharlotte Airport 16:45
      • CLTCharlotte Airport 13:54
        DTWDetroit Wayne County 18:35
      • 5h 45m (2h 51m)
      • 1 Stop CLT · Charlotte 2h 51m
      • American Airlines (AA 5175)Canadair Regional
        American Airlines (AA 1358)Boeing 737 800
      • American Airlines (AA 5175)
        • -
        • T
        • W
        • -
        • -
        • -
        • -
      • 12:50 GSP
        18:39 DTW
        5Hrs, 49m 1 Stop (CLT)
      • GSPGreenville/Spartanburg Airport 12:50 - DTW 18:39 5h 49m 1 Stop (CLT) Charlotte
      • GSPGreenville/Spartanburg Airport 12:50
        CLTCharlotte Airport 16:50
      • CLTCharlotte Airport 13:54
        DTWDetroit Wayne County 18:39
      • 5h 49m (2h 56m)
      • 1 Stop CLT · Charlotte 2h 56m
      • American Airlines (AA 5175)Canadair Regional
        American Airlines (AA 1358)Boeing 737 800
      • American Airlines (AA 5175)
        • M
        • -
        • -
        • T
        • F
        • -
        • S
      • 12:50 GSP
        18:55 DTW
        6Hrs, 05m 1 Stop (CLT)
      • GSPGreenville/Spartanburg Airport 12:50 - DTW 18:55 6h 05m 1 Stop (CLT) Charlotte
      • GSPGreenville/Spartanburg Airport 12:50
        CLTCharlotte Airport 17:07
      • CLTCharlotte Airport 13:54
        DTWDetroit Wayne County 18:55
      • 6h 05m (3h 13m)
      • 1 Stop CLT · Charlotte 3h 13m
      • American Airlines (AA 5175)Canadair Regional
        American Airlines (AA 1358)Airbus
      • American Airlines (AA 5175)
        • -
        • -
        • -
        • -
        • -
        • S
        • -
      • 13:23 GSP
        18:54 DTW
        5Hrs, 31m 1 Stop (ORD)
      • GSPGreenville/Spartanburg Airport 13:23 - DTW 18:54 5h 31m 1 Stop (ORD) Chicago
      • GSPGreenville/Spartanburg Airport 13:23
        ORDChicago O'Hare International Airport 16:36
      • ORDChicago O'Hare International Airport 14:32
        DTWDetroit Wayne County 18:54
      • 5h 31m (2h 04m)
      • 1 Stop ORD · Chicago 2h 04m
      • American Airlines (AA 3918)Embraer 170
        American Airlines (AA 3936)Embraer 170
      • American Airlines (AA 3918)
        • M
        • -
        • -
        • -
        • -
        • -
        • -
      • 13:26 GSP
        18:54 DTW
        5Hrs, 28m 1 Stop (ORD)
      • GSPGreenville/Spartanburg Airport 13:26 - DTW 18:54 5h 28m 1 Stop (ORD) Chicago
      • GSPGreenville/Spartanburg Airport 13:26
        ORDChicago O'Hare International Airport 16:36
      • ORDChicago O'Hare International Airport 14:40
        DTWDetroit Wayne County 18:54
      • 5h 28m (1h 56m)
      • 1 Stop ORD · Chicago 1h 56m
      • American Airlines (AA 4540)Embraer Emb 175
        American Airlines (AA 3936)Embraer 170
      • American Airlines (AA 4540)
        • -
        • -
        • -
        • T
        • F
        • -
        • S
      • 14:35 GSP
        18:35 DTW
        4Hrs, 00m 1 Stop (CLT)
      • GSPGreenville/Spartanburg Airport 14:35 - DTW 18:35 4h 1 Stop (CLT) Charlotte
      • GSPGreenville/Spartanburg Airport 14:35
        CLTCharlotte Airport 16:45
      • CLTCharlotte Airport 15:39
        DTWDetroit Wayne County 18:35
      • 4h (1h 06m)
      • 1 Stop CLT · Charlotte 1h 06m
      • American Airlines (AA 5275)Canadair Regional
        American Airlines (AA 1358)Boeing 737 800
      • American Airlines (AA 5275)
        • -
        • T
        • W
        • -
        • -
        • -
        • -
      • 14:35 GSP
        18:39 DTW
        4Hrs, 04m 1 Stop (CLT)
      • GSPGreenville/Spartanburg Airport 14:35 - DTW 18:39 4h 04m 1 Stop (CLT) Charlotte
      • GSPGreenville/Spartanburg Airport 14:35
        CLTCharlotte Airport 16:50
      • CLTCharlotte Airport 15:39
        DTWDetroit Wayne County 18:39
      • 4h 04m (1h 11m)
      • 1 Stop CLT · Charlotte 1h 11m
      • American Airlines (AA 5275)Canadair Regional
        American Airlines (AA 1358)Boeing 737 800
      • American Airlines (AA 5275)
        • M
        • -
        • -
        • T
        • F
        • -
        • S
      • 14:35 GSP
        20:38 DTW
        6Hrs, 03m 1 Stop (CLT)
      • GSPGreenville/Spartanburg Airport 14:35 - DTW 20:38 6h 03m 1 Stop (CLT) Charlotte
      • GSPGreenville/Spartanburg Airport 14:35
        CLTCharlotte Airport 18:48
      • CLTCharlotte Airport 15:39
        DTWDetroit Wayne County 20:38
      • 6h 03m (3h 09m)
      • 1 Stop CLT · Charlotte 3h 09m
      • American Airlines (AA 5275)Canadair Regional
        American Airlines (AA 352)Boeing 737 800
      • American Airlines (AA 5275)
        • M
        • T
        • W
        • T
        • F
        • -
        • S
      • 14:55 GSP
        18:58 DTW
        4Hrs, 03m 1 Stop (IAD)
      • GSPGreenville/Spartanburg Airport 14:55 - DTW 18:58 4h 03m 1 Stop (IAD) Washington
      • GSPGreenville/Spartanburg Airport 14:55
        IADWashington Dulles International Airport 17:15
      • IADWashington Dulles International Airport 16:29
        DTWDetroit Wayne County 18:58
      • 4h 03m (46m)
      • 1 Stop IAD · Washington 46m
      • United Airlines (UA 4959)Embraer
        United Airlines (UA 4583)Canadair Regional Jet 550
      • United Airlines (UA 4959)
        • M
        • T
        • W
        • T
        • F
        • S
        • S
      • 15:35 GSP
        20:24 DTW
        4Hrs, 49m 1 Stop (ORD)
      • GSPGreenville/Spartanburg Airport 15:35 - DTW 20:24 4h 49m 1 Stop (ORD) Chicago
      • GSPGreenville/Spartanburg Airport 15:35
        ORDChicago O'Hare International Airport 17:50
      • ORDChicago O'Hare International Airport 16:54
        DTWDetroit Wayne County 20:24
      • 4h 49m (56m)
      • 1 Stop ORD · Chicago 56m
      • United Airlines (UA 3496)Embraer 170
        United Airlines (UA 3651)Embraer 175
      • United Airlines (UA 3496)
        • M
        • T
        • W
        • T
        • F
        • -
        • S
      • 15:35 GSP
        20:24 DTW
        4Hrs, 49m 1 Stop (ORD)
      • GSPGreenville/Spartanburg Airport 15:35 - DTW 20:24 4h 49m 1 Stop (ORD) Chicago
      • GSPGreenville/Spartanburg Airport 15:35
        ORDChicago O'Hare International Airport 17:50
      • ORDChicago O'Hare International Airport 16:54
        DTWDetroit Wayne County 20:24
      • 4h 49m (56m)
      • 1 Stop ORD · Chicago 56m
      • United Airlines (UA 3496)Embraer 170
        United Airlines (UA 5259)Embraer 175
      • United Airlines (UA 3496)
        • -
        • -
        • -
        • -
        • -
        • S
        • -
      • 16:25 GSP
        20:38 DTW
        4Hrs, 13m 1 Stop (CLT)
      • GSPGreenville/Spartanburg Airport 16:25 - DTW 20:38 4h 13m 1 Stop (CLT) Charlotte
      • GSPGreenville/Spartanburg Airport 16:25
        CLTCharlotte Airport 18:48
      • CLTCharlotte Airport 17:29
        DTWDetroit Wayne County 20:38
      • 4h 13m (1h 19m)
      • 1 Stop CLT · Charlotte 1h 19m
      • American Airlines (AA 3350)Embraer Emb 175
        American Airlines (AA 352)Boeing 737 800
      • American Airlines (AA 3350)
        • M
        • T
        • W
        • T
        • F
        • -
        • S
      • 16:25 GSP
        21:36 DTW
        5Hrs, 11m 1 Stop (CLT)
      • GSPGreenville/Spartanburg Airport 16:25 - DTW 21:36 5h 11m 1 Stop (CLT) Charlotte
      • GSPGreenville/Spartanburg Airport 16:25
        CLTCharlotte Airport 19:50
      • CLTCharlotte Airport 17:29
        DTWDetroit Wayne County 21:36
      • 5h 11m (2h 21m)
      • 1 Stop CLT · Charlotte 2h 21m
      • American Airlines (AA 3350)Embraer Emb 175
        American Airlines (AA 352)Boeing 737 800
      • American Airlines (AA 3350)
        • -
        • -
        • -
        • -
        • -
        • S
        • -
      • 17:45 GSP
        21:40 DTW
        3Hrs, 55m 1 Stop (BWI)
      • GSPGreenville/Spartanburg Airport 17:45 - DTW 21:40 3h 55m 1 Stop (BWI) Baltimore
      • GSPGreenville/Spartanburg Airport 17:45
        BWIBaltimore Washington International Airport 20:00
      • BWIBaltimore Washington International Airport 19:15
        DTWDetroit Wayne County 21:40
      • 3h 55m (45m)
      • 1 Stop BWI · Baltimore 45m
      • Southwest Airlines (WN 3587)Boeing 737 700
        Southwest Airlines (WN 270)Boeing 737 800
      • Southwest Airlines (WN 3587)
        • -
        • T
        • W
        • -
        • -
        • -
        • -
      • 18:25 GSP
        00:14 DTW
        5Hrs, 49m 1 Stop (CLT)
      • GSPGreenville/Spartanburg Airport 18:25 - DTW 00:14 5h 49m 1 Stop (CLT) Charlotte
      • GSPGreenville/Spartanburg Airport 18:25
        CLTCharlotte Airport 22:25
      • CLTCharlotte Airport 19:39
        DTWDetroit Wayne County 00:14
      • 5h 49m (2h 46m)
      • 1 Stop CLT · Charlotte 2h 46m
      • American Airlines (AA 5571)Canadair Regional
        American Airlines (AA 419)Boeing 737 800
      • American Airlines (AA 5571)
        • M
        • -
        • -
        • T
        • F
        • S
        • S
      • 18:48 GSP
        23:17 DTW
        4Hrs, 29m 1 Stop (LGA)
      • GSPGreenville/Spartanburg Airport 18:48 - DTW 23:17 4h 29m 1 Stop (LGA) New York City
      • GSPGreenville/Spartanburg Airport 18:48
        LGANew York La Guardia Airport 21:16
      • LGANew York La Guardia Airport 20:42
        DTWDetroit Wayne County 23:17
      • 4h 29m (34m)
      • 1 Stop LGA · New York City 34m
      • American Airlines (AA 4370)Embraer Emb 175
        American Airlines (AA 4598)Embraer Emb 175
      • American Airlines (AA 4370)
        • M
        • -
        • -
        • -
        • -
        • -
        • -
      No Schedules Sorry, there are no schedules matching your filters. Try removing one. reset
      How far is Detroit from Greenville?

      The flight distance between Greenville and Detroit is 834km. Check all available flights on Wego.

      When is the earliest and latest flight of the day?

      The earliest flight of the day departs at 05:16. The last flight of the day departs at 19:30. See the full list of flight times on Wego.

      All Airports in Greenville

      Greenville/Spartanburg Airport GSP

      Popular Destinations From Detroit

      Popular Destinations From Greenville

      Popular Hotels in Detroit

      Hotels In Popular Destinations